the present day look at “investigated whether cannabidiol administration reduces the motivation to self-administer methamphetamine and relapse to methamphetamine-searching for behavior following abstinence.”
thirty-two male sprague dawley rats with implanted pure cbd oil vein catheters had been initially skilled to self-administer methamphetamine thru lever press at some point of two-hour periods on a fixed ratio 1 agenda of reinforcement. rats in test 1 ( n=16) then advanced to a revolutionary ratio reinforcement agenda to study the outcomes of cannabidiol (zero, 20, forty, and 80 mg/kg intraperitoneal) on motivation to self-administer methamphetamine. rats in test have been examined for cannabidiol outcomes on methamphetamine-primed reinstatement following extinction.
thirty-two male sprague dawley rats with implanted pure cbd oil vein catheters had been initially skilled to self-administer methamphetamine thru lever press at some point of two-hour periods on a fixed ratio 1 agenda of reinforcement. rats in test 1 ( n=16) then advanced to a revolutionary ratio reinforcement agenda to study the outcomes of cannabidiol (zero, 20, forty, and 80 mg/kg intraperitoneal) on motivation to self-administer methamphetamine. rats in test have been examined for cannabidiol outcomes on methamphetamine-primed reinstatement following extinction.
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